Mechanism Of Action And Clinical Use Of Metformin (siofor®): Review Of Literature


I.Yu. Demidova, T.V. Gorohova

Mechanism of action and clinical use of metformin (Siofor®): review of literature
The article is dedicated to the history of creation and mechanisms of hypoglycemic action of metformin (Siofor). The data for the metformin administration to prevent type 2 diabetes mellitus, its impact on the risk factors for cardiovascular disease are presented. The possibilities of using metformin treatment outside of type 2 diabetes (atherosclerosis, nonalcoholic steatosis, polycystic ovarian syndrome) are discussed. We consider the side effects associated with the use of metformin.

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