Биполярные расстройства: классификация, эпидемиология, диагностика и лечение

А.В. Ушкалова

Рассматривается проблема биполярных расстройств (БР) - достаточно распространенных тяжелых хронических расстройств настроения, ассоциирующихся с повышенным уровнем смертности, высокой частотой самоубийств, снижением качества жизни больных и членов их семей. Приводится классификация БР, обсуждаются их этиология и эпидемиология, проблемы диагностики. Подробно рассматриваются подходы к лечению различных форм БР. Отмечается, что соли лития, бывшие основным средством для лечения БР на протяжении ряда десятилетий, во многих случаях уступают по эффективности и безопасности противосудорожным средствам, среди которых наибольшую доказательную базу имеет вальпроат, а также атипичным нейролептикам.


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