Influence of different variants of eradication therapy on indices of non-specific colon immunity and microbiocenosis in patients with peptic ulcer disease
According to the study, including 63 patients, all patients with Helicobacter pylori (HP) associated peptic ulcer disease have moderate cellular and humoral immunity disorders. HP eradication leads to nonspecific immunological resistance normalization. Intestinal dysbiosis is detected in all patients with exacerbation of HP-associated peptic ulcer disease. The number of bifidus and lactobacillus was increased and enzimic poor E. coli growth was inhibited after HP eradication by the use of clarithromycin, amoxicillin and omeprazole.

Keywords: humoral immunity, cellular immunity, peptic ulcer disease, eradication therapy, intestinal dysbiosis