Background. Osteoarthritis (OA) accounts for 70–80% of all rheumatic pathologies, and degenerative-dystrophic changes account for 48–52%, ranking first in the number of days of disability.
Description of the clinical case. The article describes the clinical case of successful treatment of patient B., 56 years old, suffering from osteoarthritis of the joints of the hands of the 2nd stage according to Kellgren-Lawrence in combination with osteoarthritis of the intervertebral joints of the lumbosacral spine, with a tablet form of a combination of glucosamine hydrochloride 500 mg and sodium chondroitin sulfate 500 mg) according to the standard scheme: 1 tablet 2 times a day – 3 weeks, then 1 tablet per day – 2 months
Analysis of the patient’s objective data before and after treatment. During the treatment, clinical indicators that reflected the state of motor function, inflammation and pain syndrome in the joints of the hands and spine were studied. The values of the following functional indices and pain scales were assessed: the VAS scale (visual analogue pain scale), the Numeric Rating Scale (NRS-) for determining the intensity of acute pain, the Australian-Canadian functional index AUSCAN used to assess the severity of pain, stiffness in the hands and the state of joint function, as well as laboratory parameters (ESR, RF, CRP, fibrinogen) in dynamics.
Conclusion. High efficiency of a combination of glucosamine hydrochloride 500 mg and sodium chondroitin sulfate 500 mg was noted in a patient with osteoarthritis of the joints of the hands and osteoarthritis of the intervertebral joints of the lumbosacral spine. Good tolerability when taking this drug and long-term maintenance of the effect of treatment were also noted.

Keywords: osteoarthritis of the intervertebral joints, osteoarthritis of the hand joints, glucosamine hydrochloride, chondroitin sulfate