Preventive efficacy of influenza vaccines in modern conditions (literature review)


M.K. Erofeeva, V.L. Maksakova, E.V. Shakhlanskaya, Zh.V. Buzitskaya, T.I. Krainova, M.A. Stukova

Smorodintsev Research Institute of Influenza, St. Petersburg, Russia
The relevance of the influenza control is attributable to its social significance. It is generally recognized that vaccination is most effective among all medical measures implemented in the control of infectious diseases, especially airborne infections. In the World Health Organization documents, annual vaccination is recognized as the main measure for influenza epidemic control. The purpose of vaccination as a mass event is reduction in the incidence of influenza, especially its severe forms. Due to the high variability of influenza viruses and enormous damage to the national health and economy, as well as the introduction of a number of new influenza vaccines in the practice, evaluation of the effectiveness of domestic influenza vaccines is of great importance for public healthcare. Analysis of the data on the effectiveness of influenza vaccines will allow the development of a number of scientific-based measures aimed at redu-cing the incidence, hospitalization and mortality from influenza due to a more rational use of vaccines for different age categories of the population.

About the Autors

Corresponding author: Marianna K. Erofeeva, Head of the Laboratory for Testing New Means for Protection against Viral Infections, Smorodintsev Research Institute of Influenza, St. Petersburg, Russia; e-mail:
Address: 15/17, Professor Popov Street, St. Petersburg 197376, Russian Federation

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