Cough in women


DOI: https://dx.doi.org/10.18565/pharmateca.2019.5.127-132

I.L. Klyachkina

Department of Pulmonology, Russian Medical Academy of Continuous Professional Education, Moscow, Russia
A description of the pathogenesis of chronic cough (CC) in women is presented. Gender and age differences in the prevalence of CC and the sensitivity of the cough receptors are shown. The role of the female sex hormones and their effect on the cough receptors in the pathogenesis of CC is formulated. Based on the data obtained, the pathogenetic concept of CC as an independent disease is defined. Considering the difficulties of using antitussive drugs with their limited focus on either central mechanisms or peripheral receptors, such drug as Rengalin is considered, which combines antitussive, anti-inflammatory and bronchodilatory actions with the possibility of effective treatment of any type of cough in acute and chronic infectious and inflammatory allergic diseases.
Keywords: cough, cough hypersensitivity, cough receptors, vocal cord dysfunction and larynx hypersensitivity, mast cells, capsaicin, gender differences

About the Autors


Corresponding author: Irina L. Klyachkina, PhD, Associate Professor at the Department of Pulmonology, Russian Medical Academy of Continuous Professional Education, Moscow, Russia; e-mail: formozailk2012@yandex.ru
Address: 2/1, Build. 1, Barrikadnaya Street, Moscow 123995, Russian Federation


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