Difficulties in diagnosis of common variable immunodeficiency in adults in outpatient settings


DOI: https://dx.doi.org/10.18565/pharmateca.2018.13.91-94

N.V. Shabashova (1), L.V. Filippova (2), A.E. Uchevatkina (2), E.V. Frolova (2)

1) Department of Clinical Mycology, Allergology and Immunology, North-Western State Medical University n.a. I. I. Mechnikov, St. Petersburg, Russia; 2) Kashkin Research Institute of Medical Mycology, North-Western State Medical University n.a. I. I. Mechnikov, St. Petersburg, Russia
Background. To date, the number of hereditary diseases, such as genetic primary immunodeficiencies, including in adults, increases. Description of the clinical case. Two cases of common variable immunodeficiency – primary immunodeficiency, detected in female patients aged 30–31, are presented. Conclusion. Based on the data presented, it is shown that frequent prolonged inflammatory diseases of the upper respiratory tract in adults, which are resistant to traditional therapy, are the reason for studying the levels of the main classes of immunoglobulins in order to exclude primary immunodeficiency and timely prescribe an adequate immunotherapy.
Keywords: common variable immunodeficiency, hypogammaglobulinemia, primary immunodeficiency

About the Autors


Corresponding author: Ekaterina V. Frolova, Kashkin Research Institute of Medical Mycology, North-Western State Medical University n.a. I. I. Mechnikov, St. Petersburg, Russia; e-mail: labimmune@yandex.ru
Address: 1/28, Santiago de Cuba Street, St. Petersburg, 194291 Russian Federation


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