Historical, modern and perspective agents and methods of preparation of the intestine for special exams

DOI: https://dx.doi.org/10.18565/pharmateca.2018.13.8-16

M.V. Solovyev (1), R.M. Lukyanchuk (2), A.V. Gordienko (1), N.V. Sorokin (1)

1) S. M. Kirov Military Medical Academy, St. Petersburg, Russia; 2) Leningrad Regional Oncology Dispensary, St. Petersburg, Russia
The article highlights the historical background and main stages of the development of the intestinal lavage method; traditional and modern ways of assessing its effectiveness are described. Dietary recommendations and information on the main medications used at the present time for bowel preparation for to special exams are given. Based on the analysis of modern domestic and foreign guidelines and original research, including authors’ research, the prospective directions for the development of this method have been determined. It is emphasized that modern methods of antegrade intestinal lavage provide high efficiency of bowel preparation for special exams with satisfactory safety of the procedure. Polyethylene glycol-based osmotic laxatives remain optimal agents for medicamentous purgation.
Keywords: bowel preparation, lavage, colonoscopy, macrogol

About the Autors

Corresponding author: M.V. Solovyev, PhD in Medical Science, Senior Lecturer at the Department of Hospital Therapy, S.M. Kirov Military Medical Academy, St. Petersburg, Russia; e-mail: mvsol@mail.ru, ORCID: https://orcid.org/0000-0001-6832-0498
Address: 6, Akademika Lebedeva Street, St. Petersburg, 194044 Russian Federation

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