MUCOLYTICS IN THE TREATMENT OF COUGH IN CHILDREN: COMPLEXITY OF PROPERTIES


DOI: https://dx.doi.org/10.18565/pharmateca.2018.8.84-88

S.I. Shatalina, N.G. Kolosova, M.B. Aksenova, Т.V. Khlevchuk

Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia
Acute respiratory diseases continue to occupy the first place in the structure of childhood morbidity. This is associated with the large number and variability of strains of respiratory infections, as well as the periodic discovery of their new species. Cough in children is one of the most common complaints in the development of respiratory diseases. However, it is necessary to keep in mind extrapulmonary diseases that occur with the development of this symptom. In case of respiratory diseases in children, mucolytics are considered as the drug of choice in the treatment of cough. The advantage of mucolytics includes the ability to dilute sputum without increasing its quantity. Antioxidant and anti-inflammatory effects of mucolytics speed up the recovery of patients. The ability of these drugs to prevent the adhesion of bacteria to the epithelium of the upper respiratory tract and their influence on the destruction of biofilms reduce the incidence of infectious complications of acute respiratory viral infections in children.
Keywords: cough, acute respiratory diseases, children, mucolytics, acetylcysteine

About the Autors


Corresponding author: S.I. Shatalina – PhD, Teaching Assistant at the Department of Children Diseases of the Faculty of General Medicine, Sechenov First Moscow State Medical University (Sechenov University), Moscow, Russia; e-mail: svetlanashatalina@mail.ru, ORCID: https://orcid.org/0000-0003-2085-0021, Scopus Author ID: https://www.scopus.com/authid/detail.uri?authorId=57194344378


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