WHAT DOES PEDIATRICIAN NEED TO KNOW ABOUT DIAGNOSIS AND TREATMENT OF INFECTIOUS DIARRHEA


DOI: https://dx.doi.org/10.18565/pharmateca.2018.2.22-26

I.N. Zakharova, I.V. Berezhnaya, N.G. Sugyan

Russian Medical Academy of Continuous Professional Education, Moscow, Russia
The development of an infectious disease in a child is the most frequent reason for contacting a pediatrician. According to Rospotrebnadzor, there is a clear tendency to increase the incidence of diarrheal diseases by about 6–7% per year, which amounts 470–530 thousand cases in children in the Russian Federation. According to the results of Russian pharmaco-epidemiologic studies, it is shown that 72–100% of hospitalized children with diarrheal syndrome were prescribed antibiotics at once. Chloramphenicol, inhibitor-protected penicillins, rifampin, III generation cephalosporins are most widely used in hospitals, and 2/3 of patients have no indications for their prescription. The international guidelines, the terms «diarrhea», «diarrheal syndrome» and «acute gastroenteritis» are often used interchangeably, because in acute intestinal infections vomiting occurs in parallel with diarrhea. Since 2014, ESPGHAN Consensus (2014 with Amendments 2015) on management of acute gastroenteritis in children has been using in Russia. The article reviews recommendations of international and Russian experts on the therapy of diarrheal diseases in children from the point of view of evidence-based medicine.
Keywords: diarrhea, vomiting, diarrheal diseases, acute gastroenteritis, children, nifuroxazide, rehydration

About the Autors


Corresponding author: I.N. Zakharova – MD, Prof., Head of the Department of Pediatrics RMACPE of RMH, Moscow, Russia; e-mail: zakharova-rmapo@yandex.ru


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