CROUP SYNDROME IN CHILDREN: PREJUDICES AND EVIDENCE-BASED MEDICINE


DOI: https://dx.doi.org/10.18565/pharmateca.2018.1.15-22

A.S. Polyakova (1, 2), M.D. Bakradze (1, 2), V.K. Tatochenko (1)

1) FSAI “National Scientific and Practical Center for Children’s Health” of RMH, Moscow, Russia; 2) FSBEI HE “N.I. Pirogov Russian National Research Medical University” of RMH, Moscow, Russia
Conditions accompanied by obstruction of the upper respiratory tract play an important role among acute respiratory diseases in the children’s population. Most of them are accounted for the croup syndrome, which represents a subglotic mucosal edema, accompanied by typical clinical symptoms: inspiratory stridor, hoarseness, and rough «barking» cough. There are viral and spastic (recurrent) croups – pathogenetically different states with the same symptomatology. The drugs of choice for relief of acute laryngostenosis are oral, pa-renteral or inhalated glucocorticosteroids. The article describes possible conditions, manifested by relapses of croup, and main drugs, often used, but not effective in laryngostenosis.
Keywords: croup in children, laryngostenosis, laryngotracheitis, glucocorticosteroids, adrenalin

About the Autors


Corresponding author: A.S. Polyakova – PhD, Pediatrician at the Department of Diagnostic and Rehabilitation FSAI NSPCCH of RMH, Teaching Assistant at the Department of Faculty Pediatrics № 1 FSBEI HE RNSMU n.a. N.I. Pirogov of RMH, Moscow, Russia; tel. 8 (495) 967-14-21, e-mail: darmanyan@nczd.ru


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