ISSN 2073–4034
eISSN 2414–9128

Эффекты антидепрессантов в терапевтической практике

Матвиевская Е.Н., Богочанов В.С., Шевченко А.М.

Тверской государственный медицинский университет, Тверь, Россия

В последние годы в медицинской практике наблюдается рост интереса к антидепрессантам (АД) не только как к психо-
тропным средствам, но и как к препаратам с широким спектром системных эффектов. В статье рассматриваются ключевые действия АД различных фармакологических групп, их влияние на патогенетические звенья заболеваний бронхолегочной, сердечно-сосудистой, пищеварительной, мочевыделительной, нервной, эндокринной систем, системы крови, соединительной ткани, кожи. Особое внимание уделено применению АД при коморбидных состояниях. Приводятся данные о положительных и отрицательных, а также потенциально положительных и отрицательных эффектах препаратов в терапевтической практике. Сделан вывод о целесообразности более широкого использования АД в составе патогенетической терапии при наличии показаний с учетом индивидуального профиля пациента и возможных рисков.

Для цитирования: Матвиевская Е.Н., Богочанов В.С., Шевченко А.М. Эффекты антидепрессантов в терапевтической практике. Фарматека. 2026;33(1):171-179. DOI: https://dx.doi.org/10.18565/pharmateca.2026.1.171-179

Вклад авторов: Е.Н. Матвиевская – концепция и дизайн исследования, научное редактирование. В.С. Богочанов, А.М. Шевченко – сбор и обработка материала. Е.Н. Матвиевская, В.С. Богочанов, А.М. Шевченко – написание текста.
Конфликт интересов: Авторы декларируют отсутствие явных и потенциальных конфликтов интересов, связанных с публикацией настоящей статьи.
Финансирование: Работа выполнена без спонсорской поддержки.

Ключевые слова

антидепрессанты
коморбидность
соматические заболевания

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Об авторах / Для корреспонденции

Матвиевская Е.Н., к.м.н., доцент кафедры поликлинической терапии, Тверской государственный медицинский университет, Тверь, Россия; e.matvievskaya@list.ru, ORCID: https://orcid.org/0009-0006-6817-8077, eLibrary SPIN: 7590-9823 (автор, ответственный за переписку)
Богочанов В.С., студент 6-го курса лечебного факультета, Тверской государственный медицинский университет, Тверь, Россия; ORCID: https://orcid.org/0000-0002-2989-8753, eLibrary SPIN: 6490-7436
Шевченко А.М., студентка 6-го курса лечебного факультета, Тверской государственный медицинский университет, Тверь, Россия; ORCID: https://orcid.org/0009-0008-5546-2073

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