Efficacy and safety of testosterone drugs in the treatment of hypogonadism in men
The article presents current state of hypogonadism problem, in particular its age forms; the role of the hypogonadism in the development of sexual function disorders in men is presented. We discuss the relationship of hypogonadism with somatic disorders, including cardiovascular disease, type 2 diabetes mellitus, and metabolic syndrome. We consider testosterone drugs that currently use for the treatment of hypogonadism and erectile dysfunction. We particularly discuss the problem of hormonal replacement therapy safety using testosterone drugs, particularly its impact on the risk of prostate cancer development.

Keywords: androgens, hypogonadism, prostate-specific antigen, prostate cancer, erectile dysfunction, testosterone