Potential for medicamental thrombolysis in the treatment of patients with ischemic stroke
The elaboration of problem of intensive therapy of ischemic stroke is a priority for modern angioneurology. Significant number of cases of acute ischemic disorders of cerebral circulation are associated with atherothrombosis or thromboembolism of feeding vessels. The formed clot retraction or dissolution is a key task of reperfusion. Intravenous thrombolytic therapy (systemic thrombolysis) is a high effective treatment for a certain group of patients with ischemic stroke. Authors discuss the data for clinical studies of thrombolytic therapy of ischemic stroke with recombinant tissue plasminogen activator (rt-PA); the current recommendations on its use are presented.

Keywords: recombinant tissue plasminogen activator (rt-PA), intravenous thrombolysis, ischemic stroke, intracranial hemorrhages