This article presents a case of clinical observation of a patient with a rare form of deep streptostaphyloderma - chronic ulcerative pyoderma. This disease is characterized by ulcerative areas of skin lesions with histological features of pseudoepitheliomatous hyperplasia and chronic granulomatosis. The causative agents of the disease are most often Staphylococcus aureus and group A streptococci. Dermatosis often develops in patients with ulcerative colitis, alcoholism, lymphoma and other immunodeficiency conditions. Deficiency of the T-immune system, decrease in chemotaxis and phagocytic activity are detected in patients. Diagnosis of this disease is based on clinical, histological and microbiological research methods. Clinical observation of this case is of interest to practicing dermatovenerologists.

Keywords: granulating inflammation, chronic ulcerative pyoderma, microbiological study