Solid pseudopapillary tumor (SPPT) is a rare low-grade neoplasm. It accounts for 6% of all exocrine pancreatic tumors and 0.2–2.7% of the total number of malignant neoplasms. Microscopically, it is characterized by monomorphic epithelial cells with impaired intercellular adhesion, resembling pseudopapillary and solid structures. Such tumors often undergo hemorrhage and cystic degeneration. In 90% of cases, SPPT occurs in women aged 22–35 years. It also occurs in children, mostly girls, and men, with mean age of 25–40 years. According to the clinical observations conducted by I.N. Sokolova et al., the clinical presentation is most often absent, and in rare cases it can be mild or atypical. The most common complaints are pain, nausea, vomiting and abdominal discomfort. The prognosis for this diagnosis is favorable, and most patients are completely cured without relapse after surgery. In this article, we describe a clinical case of a 36-year-old woman with a massive retroperitoneal tumor.

Keywords: solid pseudopapillary tumor, β-catenin, immunohistochemical study