Retrospective analysis of the frequency of recurrent endometrial polyps in women in the reproductive period using hospital-replacing technologies


DOI: https://dx.doi.org/10.18565/pharmateca.2023.4-5.84-89

O.P. Vinogradova, M.V. Petrova, O.B. Shvetsova, M.V. Kovylina, E.N. Kalmakova, M.E. Barakova-Bezuglaya

1) Penza Institute for Postgraduate Medical Education – Branch of RMACPE, Penza, Russia; 2) Industrial Clinical and Diagnostic Center of PAO Gazprom, Moscow, Russia
Background. According to statistics, the frequency of recurrence of endometrial polyps (EP) is 25.9–78%. Despite the knowledge of the pathology, the diagnosis of RP is confirmed histologically only in 50–82% of cases [5, 8, 14]. One of the urgent problems of modern gynecology is to improve the efficiency of diagnosing endometrial pathology on an outpatient basis, clarifying the causes and preventing relapses.
Objective. Identification of the frequency of EP recurrence in patients of reproductive age, evaluation of the existing diagnostic methods and identification of possible causes of EP recurrence based on a retrospective analysis.
Methods. A retrospective analysis of the case histories of 1356 patients (mean age 47.8±0.6 years) with a diagnosis of EP over a three-year period, followed by an analysis of the case histories of 246 women of reproductive age (mean age 36.6±0.8) and 52 patients of reproductive age with EP recurrence was carried out.
Results. According to the data obtained from all observed patients with EP, 18.1% were women of reproductive age. At the same time, the frequency of EP recurrence in the examined women of reproductive age was 21.2% (52 patients). In 14 (26.9%) patients, a relapse occurred on the background of hormonal therapy. Also, 25% of the examined patients had a combination of relapse with a hyperplastic process of the genitals: adenomyosis, uterine myoma, endocervical polyp. At the same time, extragenital pathology, most often pathology of the thyroid gland, was revealed in all examined women.
Conclusion. In the diagnosis of EP, office hysteroscopy and ultrasound provide a high percentage of concurrence of diagnoses, in addition, office hysteroscopy is effective in diagnosing concomitant intrauterine pathology. In the presence of ultrasound diagnostics and office hysteroscopy in the diagnosis of pathology of the uterine cavity, priority should be given to office hysteroscopy due to the accuracy of diagnosis and the possibility of obtaining a biopsy for histological confirmation of the diagnosis. EP recurrence in women of reproductive age was noted in 21.2% of cases. In every fourth patient, a relapse occurred against the background of combined hyperplastic processes of the genitals, as well as against the background of hormonal therapy or hormonal contraception.

About the Autors


Corresponding author: Margarita V. Petrova, External Doctorate Student at the Department of Obstetrics and Gynecology, Penza Institute for Postgraduate Medical Education – Branch Campus of the RMACPE; Obstetrician-Gynecologist, Industrial Clinical and Diagnostic Center of Gazprom (Moscow), Russia; margo7alexeipetrovy@ramler.ru


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