Successful surgical treatment of mediastinal germ cell tumor against the background of chemoresistance


DOI: https://dx.doi.org/10.18565/pharmateca.2022.11-12.147-151

G.A. Khakimov, G.G. Khakimova, Zh.B. Sadullaev, A.M. Khakimov, Kh.U. Musurmonov, Kh.N. Abdullaeva, O.O. Rasulov

1) Tashkent Pediatric Medical Institute, Department of Oncology, Pediatric Oncology, Tashkent, Uzbekistan; 2) Tashkent city branch of the Republican Specialized Scientific and Practical Center of Oncology and Radiology, Tashkent, Uzbekistan; 3) Nano Medical Clinic, Tashkent, Uzbekistan
Background. Mediastinal teratoma is a rare germ cell tumor. The mediastinum is the most common extragonadal localization. Malignant tumors of the mediastinum account for 4% of all extragonadal tumors (EGT) of the mediastinum.
Description of the clinical case. We present a case of successful surgical treatment of a 24-year-old man with an immature giant mediastinal teratoma complicated by severe cardiorespiratory disorders.
Conclusion. Total replacement of the anterior mediastinum with a massive tumor extending into the thoracic cavity, which is accompanied by dystopia of the cardiopulmonary complex, as well as the high vascularity of the tumor, is not a reason for refusing surgical intervention.

About the Autors


Corresponding author: Gulnoz G. Khakimova, Cand. Sci. (Med.), Teaching Assistant at the Department of Oncology, Pediatric Oncology, Tashkent Pediatric Medical Institute, Tashkent, Uzbekistan; hgg_doc@mail.ru, https://orcid.org/0000-0002-4970-5429


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