Optimization of the differential diagnostic department in the structure of a modern tuberculosis dispensary

DOI: https://dx.doi.org/10.18565/pharmateca.2022.10.78-83

N.A. Samorodov, T.I. Bonkalo, L.I. Rubushkova, Zh.Kh. Sabanchieva, A.V. Romanova, E.I. Dubrovinskaya

1) Tuberculosis dispensary, Nalchik, Russia; 2) Research Institute of Healthcare Organization and Medical Management, Moscow, Russia; 3) Kabardino-Balkarian State University n.a. Kh.M. Berbekov, Nalchik, Russia; 4) Russian State Social University, Moscow, Russia; 5) Moscow State University of Technology and Management n.a. K.G. Razumovsky, Moscow, Russia
Background. The article is devoted to the problem of optimization of the differential diagnostic department (DDD) of tuberculosis dispensary.
Objective. Analysis and search for ways to optimize the scientific and practical activities of DDD in the structure of the tuberculosis dispensary.
Methods. Microbiological research methods were used, such as fluorescent microscopy, cultural method (inoculation of biological material in liquid and solid nutrient media), polymerase chain reaction to detect DNA of mycobacterium tuberculosis and histological examination.
Results. From 2016 to 2020, 1566 patients with suspected respiratory tuberculosis were examined at the DDD of the Tuberculous Dispensary of the Ministry of Health of the Kabardino-Balkarian Republic; the diagnosis was verified etiologically in 1246 (79.6%) patients, 296 (18.9%) patients refused additional examination for various reasons and were discharged from the department without clarifying the diagnosis, the etiology of the disease could not be verified in the dispensary in 17 (1.1%) patients, and they were referred to specialized federal centers for additional examination, and 7 (0.4%) patients died from causes unrelated to diagnostic procedures. Conclusion. it is advisable to organize DDD in the structure of the tuberculosis service of the constituent entities of the Russian Federation in order to conduct early differential diagnosis of tuberculosis and increase the number of patients with an etiologically confirmed diagnosis.

About the Autors

Corresponding author: Tatyana I. Bonkalo, Dr. Sci (Psychol.), Professor, Research Institute of Healthcare Organization and Medical Management, Moscow, Russia; 89151479832@mail.ru

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