Do we know all about acetylcysteine?


DOI: https://dx.doi.org/10.18565/pharmateca.2021.10.103-110

I.L. Klyachkina

Russian Medical Academy of Continuous Professional Education, Department of Pulmonology, Moscow, Russia
Symptomatic therapy, including antipyretics, plays center stage in the treatment of the new coronavirus infection COVID-19. The safest drug is paracetamol, which is included in outpatient treatment regimens for a new coronavirus infection (COVID-19). Paracetamol is considered a well-tolerated drug, however, despite this fact, there is a steady increase in the number of reported cases of paracetamol-induced hepatic intoxication worldwide every year. N-acetylcysteine (NAC) is approved by FDA and therefore recognized by the WHO as an essential drug widely used in the treatment of paracetamol (acetaminophen) overdose.
Keywords: paracetamol, hepatotoxicity, COVID-19, acetylcysteine

About the Autors


Corresponding author: Irina L. Klyachkina, Cand. Sci. (Med.), Associate Professor at the Department of Pulmonology, Russian Medical Academy of Continuous Professional Education, Moscow, Russia; formozailk2012@yandex.ru
Address: build. 1, 2/1 Barrikadnaya st., Moscow 125993, Russian Federation


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