Rational approach to the treatment of cough in children

DOI: https://dx.doi.org/10.18565/pharmateca.2019.11.60-68

L.A. Zhelenina, A.S. Nezabudkina

St. Petersburg State Pediatric Medical University, St. Petersburg, Russia
Background. Cough is the most common reason for parents to take their child to a pediatrician. The choice of cough therapy relies heavily on the underlying reason for the condition. Cough in pediatric patients is most frequently caused by acute respiratory diseases (ARD). Pediatricians now have a wide range of cough medicines with multidirectional mode of action at their disposal. Over the past several years, herbal medicine has been gaining popularity in treatment of ARD with cough.
Objective: to compare the efficiency and safety of multi-agent (Doctor MOM® syrup) and single-agent (Prospan® syrup) herbal drugs with those of a synthetic mucoactive drug (Ambroxol® syrup).
Methods. The study population consisted of children (n=90) with clinical presentation of acute tracheal bronchitis. A scoring system was employed to assess both efficiency and safety of treating patients with the agents named above.
Results. Efficiency of treatment with the multi-agent herbal drug was higher than that of the single-agent herbal drug and the synthetic mucoactive drug, which can be explained by a more apparent anti-inflammatory effect of its herbal ingredients. According to the assessment by the patients` parents, herbal drugs were safer than the synthetic mucoactive drug.
Conclusion. Doctor MOM® syrup is an efficient and safe antitussive and anti-inflammatory drug that can successfully treat cough in children with ARD.
Keywords: cough, phytotherapy

About the Autors

Corresponding author: Lyudmila A. Zhelenina, MD, Professor of the Pediatric Department named after Igor’ M. Voroncov, Saint-Petersburg Medical Pediatric University, Saint-Petersburg, Russia; e-mail: jelenina@mail.ru; ORCID: https://orcid.org/0000-0001-8474-5154; eLibrary SPIN: 3893-1637
Address: 2, Litovskaya Street, St. Petersburg 194100, Russian Federation

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