RELATIONSHIP BETWEEN THYROID STATUS AND PARAMETERS OF DAILY BLOOD PRESSURE MONITORING IN PATIENTS WITH ARTERIAL HYPERTENSION


DOI: https://dx.doi.org/10.18565/pharmateca.2018.10.43-45

A.A. Feskova, A.Ya. Kravchenko

Voronezh State Medical University n.a. N.N. Burdenko, Voronezh, Russia
Background. Arterial hypertension (AH) is one of the most important and common risk factors for cardiovascular complications. According to the data of a number of studies, various disorders of the thyroid gland function have an impact on the cardiovascular system. Objective. Evaluation of the relationship between thyroid status parameters and the blood pressure (BP) level in persons with AH. Methods. 180 patients with essential AH aged 53.1±9.5 years were examined. Patients underwent thyroid status examination and 24-hour BP monitoring. Results. A direct correlation of thyroid-stimulating hormone level with average daily systolic (SBP) and diastolic blood pressure (DBP), mean BP and with a degree of nocturnal BP decrease (DNBPD) was revealed; inverse correlation of free T3 with average daily SBP, DBP, with mean BP, and direct correlation – with DNBPD were established. Direct correlation of free Т4 and DNBPD was noted. Conclusion. The revealed correlations of the thyroid status parameters, in particular TSH, with the 24-hour BPM datA suggest their participation in the regulation of vascular tone through influence on pressor and depressor mechanisms.
Keywords: thyroid-stimulating hormone, thyroid hormones, arterial hypertension, blood pressure, daily blood pressure profile

About the Autors


Corresponding author: A.A. Feskova – PhD, Teaching Assistant at the Department of Faculty Therapy, Voronezh State Medical University n.a. N.N. Burdenko, Voronezh, Russia; e-mail: annushkafeskova@yandex.ru


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