MICROBIOTA, METABOLIC SYNDROME, PSYCHO-INTELLECTUAL FUNCTIONING: BORDERLINES OF PATHOGENETIC CONJUGATION


DOI: https://dx.doi.org/10.18565/pharmateca.2018.9.24-31

Yu.A. Fominykh (1), Yu.P. Uspensky (1, 2)

1) Pavlov First St. Petersburg State Medical University, Saint-Petersburg, Russia; 2) St. Petersburg State Pediatric Medical University, Saint-Petersburg, Russia
The article presents the results of analysis of modern scientific medical literature on the relationship between microbiota and metabolic syndrome, their impact on the psycho-intellectual status of patients. Given that the nervous system and psycho-intellectual functioning are adversely affected by both the signal molecules produced by the microbiota and the metabolic abnormalities, it is advisable to consider these disorders within the framework of a single pathological process with common clinical and pathogenetic links. An integrated approach to this complex pathology within the framework of current trends in the development of medical science will contribute to more adequate and effective management of such category of patients.
Keywords: microbiota, metabolic syndrome, psycho-intellectual status, nervous system, signaling molecules

About the Autors


Corresponding author: Yu.A. Fominykh – PhD, Associate Professor, Associate Professor at the Department of Internal Diseases of the Faculty of Dentistry, Pavlov First St. Petersburg State Medical University, St. Petersburg, Russia; tel. +7 (812) 555-47-62, e-mail: jaf@mail.ru


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