THE ROLE OF ACUTE INTESTINAL INFECTIONS OF VIRAL ETIOLOGY IN THE DEVELOPMENT OF FUNCTIONAL PATHOLOGY OF THE GASTROINTESTINAL TRACT IN CHILDREN


K.D. Ermolenko (1, 2), N.V. Gonchar (1, 4), E.I. Ermolenko (3, 5), M.A. Suvorova (3), E.A. Tarasova (3), M.P. Kotyleva (3), Yu.V.Lobzin (1, 4)

(1) FSBI Scientific Research Institute of Children's Infections FMBA, St Petersburg; (2) SRI of Epidemiology and Microbiology n.a. Pasteur, Saint-Petersburg; (3) FSBIS Institute of Experimental Medicine, St. Petersburg; (4) Northwestern State Medical University n.a. I.I. Mechnikov, Saint Petersburg; (5) St. Petersburg State University, St. Petersburg
The article presents the results of studies of the functional disorders of the gastrointestinal tract (GIT), and changes in intestinal microbiota in 120 children who had acute intestinal infection caused by rotaviruses and noroviruses. It was shown that functional gastrointestinal pathology realized at 18.3% of convalescents after viral gastroenteritis. Changes of microbiota in viral gastroenteritis of different etiologies have a number of specific features: reducing the quantitative content of Faecalibacterium prausnitzii, raising of Bacteroides thetaiotaomicrion in rotavirus infection, pronounced inhibition of growth of Lactobacillus spp. and Bifidobacterium spp., the excessive growth of opportunistic bacteria in norovirus infection.

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About the Autors


K.D. Ermolenko – postgraduate student at the FSBI Scientific Research Institute of Children's Infections FMBA, Researcher at the department of identification of pathogens of the SRI of Epidemiology and Microbiology n.a. Pasteur, Saint-Petersburg; email: ermolenko.kd@yandex.ru


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