H1- ANTIHISTAMINES IN PEDIATRIC PRACTICE


L.R. Selimzyanova (1, 2), E.A. Vishneva (1), E.A. Promyslova (1)

(1) FSBI "Scientific Center of Children's Health", RAMS; (2) SBEI HPE First MSMU n.a. I.M. Sechenov of RMPH, Moscow
Histamine is one of the most important biogenic amines involved in many physiological and pathological processes in the human body. At the present time, 4 types of histamine receptors are recognized. H1- receptors play the most important role in the development of allergic reactions. History of use of antihistamines includes approximately 70 years. These drugs have anti-allergic and anti-inflammatory effects. Currently, the pharmaceutical market represented a sufficiently large number of antihistamines, but not all of them can be applied in children up to 6-month age. This article presents data on the histamine receptor and H1- receptor agonists used in pediatric practice: types of drugs, forms of presentation, efficiency, safety and use.

About the Autors


L.R. Selimzyanova - PhD in Medical Sciences, Senior Scientist at the Division of Clinical Pharmacology and Standardization FSBI SCCH RAMS, teaching assistant at the Department of Pediatrics and Children’s Rheumatology SBEI HPE First MSMU n.a. I.M. Sechenov of RMPH
E.A. Vishneva - PhD in Medical Sciences, Leading Researcher at the Division of Clinical Pharmacology and Standardization FSBI SCCH RAMS
E.A. Promyslova - researcher at the Division of Clinical Pharmacology and Standardization FSBI SCCH RAMS


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