ANTITUMOR EFFECTS OF SOMATOSTATIN ANALOGUES IN SOMATOTROPH PITUITARY ADENOMAS: REVIEW OF RECENT RESEARCH


M.B. Antsiferov (1), V.S. Pronin (2)

(1) SBHCI "Endocrinological Dispensary" of Moscow Healthcare Department, Moscow; (2) SBEI HPE "First Moscow State Medical University n.a. I.M. Sechenov" of RMPH, Moscow
The review is dedicated to the issues of classification, diagnosis, clinical course and methods of treatment of somatotroph pituitary adenomas. The mechanisms of the antiproliferative effect of somatostatin analogues and their potential use in the presence of absolute or relative contraindications to surgery are discussed. The results of a meta-analysis and clinical studies confirming not only antisecretory, but the antitumor effects of somatostatin analogues are presented.

About the Autors


M.B. Antsiferov – MD, Prof., Chief Doctor of the SBHCI "Endocrinological Dispensary" of Moscow Healthcare Department
V.S. Pronin – MD, Prof. at he Department of Endocrinology SBEI HPE "First Moscow State Medical University n.a. I.M. Sechenov" of RMPH; e-mail: vspronin@yandex.ru


Similar Articles


Бионика Медиа