PREDICTIVE VALUE OF PROLONGED USE OF SELECTIVE M3-CHOLINOLYTICS IN PATIENTS WITH IRRITABLE BOWEL SYNDROME


V.B. Grynevych, E.I. Sas, Yu.A. Kravchuk, N.N.Scherbina, O.I. Efimov

Military Medical Academy n.a. S.M. Kirov, St. Petersburg
The article is dedicated to the evaluation of the efficacy of antispasmodic drugs used in the treatment of patients with irritable bowel syndrome (IBS). According to the results of numerous studies, hyoscinebutylbromide has a physiological effect on the secretory and motor functions of the gastrointestinal tract, can effectively eliminate these violations and reduces the number of relapses. The authors conclude: prolonged use of hyoscinebutylbromide in the complex therapy of patients with IBS is not only safe, but also prognostically justified for these patients, because it contributes the recovery of visceral sensitivity and significantly reduces the incidence of recurrence of the disease.

About the Autors


V.B. Grynevych – MD, Prof., Head of the 2nd Department of Therapy (Postgraduate Education) of the Military Medical Academy n.a. S.M. Kirov
E.I. Sas – MD, Prof. at the 2nd Department of Therapy (Postgraduate Education) of the Military Medical Academy n.a. S.M. Kirov
Yu.A. Kravchuk – PhD in Medical Sciences, Prof. at the 2nd Department of Therapy (Postgraduate Education) of the Military Medical Academy n.a. S.M. Kirov
N.N.Scherbina - Assoc. Prof. at the 2nd Department of Therapy (Postgraduate Education) of the Military Medical Academy n.a. S.M. Kirov
O.I. Efimov – PhD in Medical Sciences, Teaching Assistant at the 2nd Department of Therapy (Postgraduate Education) of the Military Medical Academy n.a. S.M. Kirov


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