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A.I. Parfenov, A.V. Karlov

Moscow Clinical Scientific Practical Center. Central Scientific Research Institute of Gastroenterology of Moscow Healthcare Department, Moscow
The article describes the current data on the prevalence, causes, diagnosis and treatment of functional bowel disturbance - loss of the ability of the rectum to retain feces. The mechanism of action of superselective 5-HT4 receptor agonists, allowing to achieve control on the function of defecation are described.

About the Autors


Parfenov A.I. - Prof., MD, Head of the Division of Pathology of Bowel, Moscow Clinical Scientific Practical Center. Central Scientific Research Institute of Gastroenterology of Moscow Healthcare Department, e -mail: asfold@mail.ru;
Karlov A.V. – Head of Laboratory of functional bowel disturbances, Moscow Clinical Scientific Practical Center. Central Scientific Research Institute of Gastroenterology of Moscow Healthcare Department.


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